Enzyme immunoassay for the quantitative determination of Rituximab (Rituxan®, Mabthera®) in human serum and plasma
This kit has been especially developed for the quantitative determination of rituximab in serum and plasma samples between the Cmin and Cmax range of concentrations.
Rituximab Drug Bank Accession Number is DB00073
Rituximab is a monoclonal anti-CD20 antibody used to treat non-Hodgkin"s lymphoma, chronic lymphocytic leukemia, Wegener"s granulomatosis, pemphigus vulgaris, and rheumatoid arthritis.
Measurement of biological drug trough levels and antibody to biological drug gained high importance during the course of treatment. Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences. Measurement of biological drug trough levels and antibody to biological drug gained high importance during the course of treatment. These measurements enable dose adjustments and switch to another class of biological drug when necessary.
All SHIKARI® ELISA kits are suitable for biosimilar work.
